I really like what they did with the look of UM in the 22.04 LTS. All they need to do is come up with some different desktop layouts like Ubuntu Mate does (and Zorin & Manjaro GNOME) to knock it out of the park. COSMIC is a more logical and efficient version of GNOME to me which works better. But i am liking what System76 did with the GNOME desktop making it their own spin with the Computer Operating System Main Interface Components (COSMIC) desktop. These issues may not affect you and that's great if so. So, Pop!_OS makes sense for me (even though I really like UM and Manjaro too). By doing so you might make a reliable distribution less reliable maybe than Arch. You can remove Snap integration but I just don't want problems later on if something breaks. But by default when you look for software in the respective stores, they offer Snaps first and Ubuntu and/or Debian as a 2nd/3rd alternative. Hmm, I thought that CUPS and IPP support had been installed in the full image. ("snap list" in the terminal) That's not so bad. You can open up the terminal and see that each distribution in the Ubuntu community (Ubuntu, Kubuntu, Xubuntu, Lubuntu, Ubuntu MATE, UbuntuStudio) have a handful of applications based on Snaps. Some of the core elements in the distribution are Snaps too like the Software Boutique. PPA maybe better, but they chose Snap.įirefox by default is a Snap in Ubuntu distributions. So having CUPS as a Snap is a good idea, if we or Canonical care about the users. This is upstream (Ubuntu) decision targeted on user comfort.įor example CUPS provides drivers for printers which are released very fast (faster than LTS release cycle of course). Ubuntu-release-upgrader-gtk* update-manager* update-notifier*Ġ upgraded, 0 newly installed, 51 to remove and 54 not upgraded.Īfter this operation, 144 MB disk space will be freed. Squashfs-tools* ssl-cert* ubuntu-mate-core* ubuntu-mate-desktop* Rtkit* snapd* software-properties-common* software-properties-gtk* Python3-reportlab* python3-reportlab-accel* python3-software-properties* Python3-debconf* python3-olefile* python3-pil* python3-renderpm* Pulseaudio-module-bluetooth* pulseaudio-utils* python3-dateutil* Printer-driver-postscript-hp* printer-driver-splix* pulseaudio* Libspeexdsp1* printer-driver-gutenprint* printer-driver-hpcups* Libimagequant0* libpulsedsp* libsane-hpaio* libsbc1* libsnapd-glib1* Libcupsimage2* libgutenprint-common* libgutenprint9* libhpmud0* Gir1.2-goa-1.0* gir1.2-snapd-1* hplip* hplip-data* libcanberra-pulse* Is safe, but $ sudo apt autopurge gir1.2-snapd-1:amd64 libsnapd-glib1:amd64 snapdĪpturl* apturl-common* ayatana-indicator-sound* bluez-cups* cups*Ĭups-browsed* cups-core-drivers* cups-daemon* cups-server-common* Now I see that $ sudo apt autopurge snapdĠ upgraded, 0 newly installed, 2 to remove and 54 not upgraded.Īfter this operation, 94,3 MB disk space will be freed. That is a problem if you want to purge snapcraft completly.
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5/14/2024 0 Comments Whiskey bent and hellbound tankOnce the customer receives the purchased product from our website and the product received is not the right ordered merchandise or physically damaged due to an error on our part or the sellers, Artist Shot will contact the seller to address the issue for the replacement of the product after receiving reasonable proof of the issue from the buyer. There are no refunds or exchanges after an order has been printed and/or shipped under any circumstances. Orders are processed as early as minutes after they are placed on Artist Shot. Fifteen percent cancellation fee includes costs associated with preparing for an order, including artwork processing, prepress processing, and material preparation costs. Orders enter the printing process as early as same day or next business day after the order has been placed on the website.Ĭancellation on orders before printing begun can be done with to a fifteen percent (15%) cancellation fee of the order total. Once a printing of a product begins, cancellation cannot be performed. You may not cancel an order once it has been submitted unless informed otherwise. Artist Shot take no accountability for any product the customer does not obtain due to incorrect address provided for shipment to Artist Shot. It is the buyers/users/customers obligation to provide the correct delivery shipment address. In a delinquency of payment from the customer, Artist Shot has the right o transfer the claims to a debt collection agency along with personal information needed for the handling of payments to third parties. The cost of the product will be charged at the time your order is placed.Īrtist Shot have to right to rely on trustworthy third party services for handling of the payment. The price of the purchased product is fixed at the time of the ordering. If such a cancellation occurs after the customer has made a payment for the product, the charged amount will be refunded back to customer's account.īuyers/Users can purchase products on the Artist Shot website using a valid credit card or the PayPal system and do not have to be a member to purchase a product. We retain this right until the time customer receives the product ordered. Purchased product order may be canceled even of it has been confirmed and the customer has made payment. Artist Shot also may cancel an order if it is believed to violate this agreement or in infringement of the right of any person or any law. If the buyer has already made a payment, the payment shall be refunded.Īrtist Shot maintains the right to deny any given orders for any reason with notice to the customer. If Artist Shot fails to comprise the unavailable product in a business timeframe, the buyer shall be informed immediately about the non-availability of the product and the service. Artist Shot will attempt to replace the product with an identical substitute transaction if any disruption of shipment of the product occurs. The contract becomes terminated with full delivery to the address provided by the buyer to Artist Shot. The contract is only accepted and becomes active when Artist Shot ships the ordered product to the buyer and confirms the shipment of the product to the buyer in a second e-mail. This e-mail validates and shall only inform the buyer that their order was received by Artist Shot and does not suggest an approval of the offer. The buyer then will receive an e-mail with the order confirmation. The proposals offered on Artist Shot and in partner shops on the website serve a non-binding request for the customer to purchase an order with Artist Shot.īy completing an order application and sending the request to purchase a "product" on the Artist Shot website, the buyer makes a binding offer for a contract of sale of the content product offered on the website. This 5 piece kit includes a durable storage bag with a wide, zippered opening, a flat sandalwood beard comb, beard butter, beard oil, and bar soap all in a convenient, compact size.Standard Terms for Purchasing/Returning a Product on Artist Shot Keeping your beard game strong whether your tearing up the asphalt or kicking back at a roadside dive, the Whiskey Bent & Hellbound Travel Beard Kit is packed to the brim with all your grooming essentials. 5/14/2024 0 Comments Pac man world 2 rom gamecubeThe game includes several mazes, each with a different layout. Not much to say about these the gameplay in these mazes is almost identical to the original Pac-Man game. You can find Galaxians in the levels, which unlock doors that transport you to traditional Pac-Man mazes. Pac-Dot Chains also appear in the sequels. This allows him to reach items that are otherwise impossible to get, and reach other areas of a level. If Pac-Man eats the red dot, he basically flies in a set path and follows the Pac-Dots. After pressing certain switches, Pac-Dots appear forming a path. One of my favorite features are the Pac-Dot Chains. Even though this game has a larger emphasis on platforming, it still has some traditional Pac-Man gameplay and features. Like other Pac-Man games, there are Power Pellets that can be collected and allow you to go after the ghosts. The ghosts make appearances in some areas of each level. This power-up appears in the sequels as well. There's also a Chrome/Steel Ball power-up that allows Pac-Man to walk underwater and break open chests. Fruit can be out in the open and hidden in chests. Pac-Man has a few different moves, such as the butt-bounce (useful for defeating enemies and opening chests) and a rev roll (can be used to get up steep hills).Ĭollecting fruit unlocks doors which contain switches and letters that spell "PACMAN", giving you more to do in each level. You can throw the dots you've collected at enemies. But like most other Pac-Man games, you still collect dots and fruit. In this game, the main villain is a robot character named Toc-Man. He's gonna pay for capturing Pac's family and ruining his Birthday. All of the Pac-Man World games have their own villains besides the ghosts. Pac-Man and Pac-Baby, are nowhere to be found. But he finds that his house is a mess, and Ms. It's Pac-Man's Birthday, and he arrives home from work excited about his big day. The GBA version has sprites and a side-scrolling/isometric view, but does its best to recreate some of the levels from the PlayStation version. The game has updated versions of music from both the original Pac-Man and Ms. It has several nods and tributes to several Namco Arcade games, like Galaxian and Dig Dug. Originally released on PlayStation during Pac-Man's 20th Anniversary, and later for the Game Boy Advance, this was one of the first (but not the first) true 3D Pac-Man games. The Pac-Man World Series and Why I Like It This blog will focus on most versions of the Pac-Man World games (including the GBA versions of Pac-Man World 1 and 2 and the remake of the first one), and why I like the series. Most recently, the first Pac-Man World has gotten a remake (titled Pac-Man World Re-Pac) for current game systems. Each of them were released on various systems, with the first two even getting Game Boy Advance versions and the third game getting released on the Nintendo DS. While I have played all three Pac-Man World games (and the racing spin-off, Pac-Man World Rally), the first one I played was actually Pac-Man World 2 on GameCube (also released on PS2, Xbox, PC, and Game Boy Advance). But as great as traditional Pac-Man games are, there's one series of Pac-Man games that I've always appreciated because they both have traditional Pac-Man gameplay and successfully brought the character into 3D: the Pac-Man World series, consisting of three main entries, a racing game, and a remake for modern systems. Like many, I've played a lot of Pac-Man games over the years in Arcades, on consoles, handhelds, PC, etc. I mentioned in a previous blog that I might make a blog about the Pac-Man World series. 5/13/2024 0 Comments Ch4 dipole momentThis molecule has regions of high electron density that consist of two single bonds and one double bond. Lone pair > triple bond > double bond > single bond lone pair > triple bond > double bond > single bondĬonsider formaldehyde, H 2CO, which is used as a preservative for biological and anatomical specimens ( Figure 7.14). One of these regions, however, is a lone pair, which is not included in the molecular structure, and this lone pair influences the shape of the molecule ( Figure 7.18). On the other hand, the ammonia molecule, NH 3, also has four electron pairs associated with the nitrogen atom, and thus has a tetrahedral electron-pair geometry. The electron-pair geometries will be the same as the molecular structures when there are no lone electron pairs around the central atom, but they will be different when there are lone pairs present on the central atom.įor example, the methane molecule, CH 4, which is the major component of natural gas, has four bonding pairs of electrons around the central carbon atom the electron-pair geometry is tetrahedral, as is the molecular structure ( Figure 7.17). The structure that includes only the placement of the atoms in the molecule is called the molecular structure. We differentiate between these two situations by naming the geometry that includes all electron pairs the electron-pair geometry. Molecular structure describes the location of the atoms, not the electrons. The electron-pair geometries shown in Figure 7.16 describe all regions where electrons are located, bonds as well as lone pairs. It is important to note that electron-pair geometry around a central atom is not the same thing as its molecular structure. Electron-pair Geometry versus Molecular Structure The bond angle is 180° ( Figure 7.15).įigure 7.16 The basic electron-pair geometries predicted by VSEPR theory maximize the space around any region of electron density (bonds or lone pairs). With two bonds and no lone pairs of electrons on the central atom, the bonds are as far apart as possible, and the electrostatic repulsion between these regions of high electron density is reduced to a minimum when they are on opposite sides of the central atom. The Lewis structure of BeF 2 ( Figure 7.15) shows only two electron pairs around the central beryllium atom. Other interactions, such as nuclear-nuclear repulsions and nuclear-electron attractions, are also involved in the final arrangement that atoms adopt in a particular molecular structure.Īs a simple example of VSEPR theory, let us predict the structure of a gaseous BeF 2 molecule. We should understand, however, that the theory only considers electron-pair repulsions. VSEPR theory predicts the arrangement of electron pairs around each central atom and, usually, the correct arrangement of atoms in a molecule. The electrostatic repulsion of these electrons is reduced when the various regions of high electron density assume positions as far from each other as possible. The electrons in the valence shell of a central atom form either bonding pairs of electrons, located primarily between bonded atoms, or lone pairs. The VSEPR model assumes that electron pairs in the valence shell of a central atom will adopt an arrangement that minimizes repulsions between these electron pairs by maximizing the distance between them. Valence shell electron-pair repulsion theory (VSEPR theory) enables us to predict the molecular structure, including approximate bond angles around a central atom, of a molecule from an examination of the number of bonds and lone electron pairs in its Lewis structure. Figure 7.14 Bond distances (lengths) and angles are shown for the formaldehyde molecule, H 2CO. 5/13/2024 0 Comments Kyzikos electrum coinsConsiderably better style portrait than usual. Near EF, attractively toned, minor die wear on obverse. 54, dies D115/R1, a = Davis Collection 193 (this coin) SNG Copenhagen Ð SNG von Aulock Ð McClean 7544 var. Diademed head and epithet of Nikomedes II right / Zeus Stephanophoros standing left to inner left, eagle standing left on thunderbolt above monogram and H(koppa)P monogram (date). 128-94 BC (portraits and epithets those of Nikomedes II)ġ1281.ěITHYNIA, KINGS, NIKOMEDES III EPIPHANES. VF, toned, short flan crack, light marks and scratches. Kaye Series D, 40-1 (unlisted dies) RG 10 HGC 7, 623. Head right with slight beard, wearing winged diadem / Zeus Stephanophoros standing left to inner left, eagle standing left on thunderbolt above monogram. Provenance: Ex Classical Numismatic Group Electronic Auction 291 (21 November 2012), lot 65.ġ3030.ěITHYNIA, KINGS, PRUSIAS II KYNEGOS. VF, toned, wavy flan, test punch on obverse, light marks and scratches. Diademed head right / Zeus Stratios standing left, holding scepter to inner left, thunderbolt above two monograms. 255-228 BC, (very few coins and only in bronze)ġ2876.ěITHYNIA, KINGS, PRUSIAS I CHLOROS. A wonderful depiction of one of the major Greek myths. Reverse: NIKAIΩN Triptolemos naked driving a chariot pulled by two giant winged serpents left. Obverse: Hades seated three quarter facing on his throne in the underworld holding his scepter, the abducted Persephone standing to his right facing left traces of an unknown legend around. EXTREMELY RARE GREEK MEDALLION OF PERSEPHONE IN HADES, Asia Minor, c. found in the example above 8193, and the bull is priapic as well! Bithynia was the birthplace of Antinous and Theodosius.ġ0367.ěITHYNIA, NIKAIA. A much more robust and impressive bull of better artistic quality than normal as e.g. A very rare coin, especially with the more classic square incuse dotted reverse! Nicer in hand than the photos show. Quartered square incuse with raised dots. Bull standing on corn ear, caduceus before. The obverse one of the great masterpieces of Greek numismatic art.ġ0143.ěITHYNIA, KALCHEDON WITH PRIAPIC BULL, early 4th century BC. Struck on an especially large medallic flan. Laureate head of Apollo right / Apollo Grynios standing right, holding branch and phiale monogram to left, omphalos and amphora at feet to right all within laurel wreath. The obverse one of the great masterpieces of Greek numismatic art.ġ1030.ĚEOLIS, MYRINA, Circa 155-145 BC. Laureate head of Apollo right / Apollo Grynios standing right, holding branch and phiale monogram to left, omphalos and amphora at feet all within laurel wreath. A portrait of exquisite sensual style of a highly voluptuous Greek nymph.ġ0785.ĚEOLIS, MYRINA, Circa 155-145 BC. die 57 SNG Copenhagen - BMC 77 (same obv. Head of the Amazon Kyme right, wearing tainia / Horse prancing right one-handled cup below, EYKTHMΩN in exergue all within wreath. 5/13/2024 0 Comments Smultron mattaThey will spread and colonise an area of ground through runners, but they will also self-seed on nearby ground. The berries normally first ripen in July and will continue to produce berries until September or October, depending on the weather conditions. They tend to prefer stony, lime rich where they will receive plenty of sun, but also some shade for part of the day. Wild strawberries will grow on grasslands, open areas and on the edge of forests. No doubt the owners hope that it is not too secret, but a place where ice cream lovers will be happy! Where and when? Supposedly these are secret happy places not known to most tourists! At the other extreme there is a rather good ice cream parlour in Söderköping called Smultronstället. For instance, Smultronställen på Öland (Secret happy places on Öland) lists places like Gräsgårds hamn (a harbour), Mormors stenugnsbageri (a bakery) and Ölands örtagård (a herb garden). Such is the importance of smultronstället in Swedish culture that some Swedish travel writers now provide guides to smultronställen (secret happy places). Often it is somewhere near their summer cottage (most Swedes have a share in a summer cottage), but there may not be any smultron there: it is simply a secret place to relax and be happy. Nowadays many Swedes have their own private smultronställe. If literally translated, Smultronstället means The Wild Strawberry Plot, but it has now become to mean 'The Secret Happy Place'. Indeed, one of the greatest devotees of the film is Woody Allen, so if you have not seen it do try and find a copy to appreciate why he regarded it as such an important film. The film is much deeper than indicated by my brief synopsis above, but for anyone interested in Swedish culture it is essential viewing. He reflects on the fact that gathering smultron with Sara was perhaps the happiest time in his whole life. She is a double for the love of Isak's youth with whom he remembered gathering smultron. Borg sets out on a long car ride from Stockholm to Lund in order to be awarded an honorary degree. During the journey (of self-discovery) he meets a series of hitchhikers, one of whom is a woman named Sara. The main character in the film is called Professor Isak Borg, a widowed and rather grumpy 78-year-old physician. The reason that so many Swedes regard smultron with such affection is because of Smultronstället, a film written and directed by Ingmar Bergman and released in 1957. Even Vår Kokbok, Sweden's most popular cookery book, doesn't have a single smultron recipe! Smultronstället The mere mention of smultron (wild strawberries) to most Swedes is likely to produce a smile, even though they are unlikely to be their favourite berry! In truth most Swedes prefer cultivated strawberries and regard smultron as something of a novelty. Technically, you can take the exam whenever you want, but your specific scheduling usually depends on your medical school’s policies. Your eligibility comes from being enrolled at an accredited school. Students typically take USMLE Step 1 at the end of second year (MS2), USMLE Step 2 CK is typically taken at the end of third year (MS3) or during fourth year (MS4), and Step 3 is typically taken during the first year of residency. The current minimum USMLE Step 1 score to pass Step 1 is 196, and the maximum possible score is 300. The total number of questions in Step 1 will not be more than 280. While the number of questions per block may vary, they will not exceed 40. It is administered in one 8-hour testing session, which includes an optional 15-minute tutorial and 45 minutes of break time. USMLE Step 1 is a one-day exam that’s divided into seven 60 minute blocks. Special emphasis is placed on the principles and mechanisms that underlie health, disease, and modes of therapy. Step 1 organizes basic science material along two dimensions: systems and processes. The United States Medical Licensing Exam (USMLE) is a 3-part test designed to evaluate a student’s medical knowledge as well as their ability to apply that knowledge to patient care. USMLE Step 1 Study Schedule: Pre-Dedicated and Dedicated.Our Step 1 guide will dig into what the pass/fail change means for students, the best resources to use, how to create a study plan, success strategies, and FAQs. It is critical that you pass this test, and the testing skills you build during this time are what will serve you when it comes time for Step 2 and Step 3. Although USMLE Step 1 is now pass/fail, it is still an incredibly challenging exam that you shouldn’t take lightly. USMLE Step 1 was previously regarded as the most important test that future doctors take. Med School Insiders Balance & Wellness Scholarship.
5/13/2024 0 Comments Jordan 1 hyper royal 2021CONDITION: New with OG Box (perfect condition for shoes collector). His favorite hip-hop artists are Kendrick Lamar, Playboi Carti, Travis Scott, and Lil Uzi Vert. ITEM: NIKE AIR JORDAN 13 RETRO BG -White Royal. As a Montrealer, the Montreal Canadiens hold a special place in his heart, even if they haven't won the Stanley Cup in his lifetime.Īlex also works for the Concordia Stingers, where he provides play-by-play and color commentary for the football, hockey, and basketball teams His favorite teams are anywhere LeBron goes, and the Kansas City Chiefs. When it comes to sports, Alex has a particular interest in the NBA and the NFL. The latter includes the Swoosh, Jumpman tongue tag and printed Wings logo on. The sneaker’s all-leather upper combines a black base with Hyper Royal hits on the toe box, collar and the sneaker’s various branding elements. And though it’s been seen time and time again in its adult size, we’ve yet to show off the pair’s. But come later this Spring, the colorway might be outdone as the brand is soon to offer the similarly hyped Hyper Royal. Advertisement - Dressed in a Hyper Royal, Light Smoke Grey, and White color. The Air Jordan 1 University Blue was, with certainty, one of the most sought after releases of 2021 thus far. Air Jordan 1 Mid Hyper Royal Air Jordan, sneakers, Air Jordan 1. The grade school-sized Air Jordan 1 Mid Hyper Royal GS was released on 4th February 2021. The Air Jordan 1 High OG Hyper Royal will take part of Jordan Brand’s Spring/Summer 2021 lineup. Buy Air Jordan 1 Mid Hyper Royal - 554724 077 GOAT. Although his collection might not be the biggest, he is always looking to add new styles to it. The Air Jordan 1 Mid GS Black Hyper Royal offers a twist on the OG colorway of the AJ1 High. This shoes upper is attached to a black rubber outsole. His favorite kicks are the Air Jordan 1 High OG, the Air Jordan 4, the Air Jordan 6, and the Adidas Yeezy Boost 350 V2 in the "Beluga 2.0" colorway. During this time, he has shown an expertise in Air Jordans, Yeezys, and all things that have to do with Nike. He started at HotNewHipHop back in 2018 where he began as a Sports and Sneakers writer. Alexander Cole is the current Managing Editor of HotNewHipHop. 5/12/2024 0 Comments Gun jam typesTo practice clearing a jammed gun, all you need is a little range time and a dummy ammunition round. While having a misfire at the range may not be a big deal, a self-defense situation is a different story, and knowing how to safely and quickly clear your jammed gun could mean the difference between life and death. Now that you know the basics of how to clear a jammed gun, it’s time to put your knowledge to the test. Then, reinsert the magazine and rack the slide to chamber a new round. To clear a double feed, simply remove the magazine from the gun and rack the slide a few times to clear the stuck casing. This is the least common type of gun jam, but it does happen. Double FeedĪs the name implies, a double feed occurs when the gun either tries to feed two rounds into the chamber or attempts to feed a new round into the chamber when the current spent round wasn’t fully ejected. Reassess the situation and return to firing if needed. Next, rack the slide while the gun is still tilted. Start by smacking the bottom of the magazine and tilting the gun inward (use gravity to your advantage). Clearing a failure to eject is similar to clearing a failure to feed. Failure to EjectĪlso known as a stovepipe, a failure to eject occurs when the spent round gets stuck and isn’t fully ejected from the gun. Next, rack the gun, reassess the situation, and return to fire if necessary. Luckily, these types of malfunctions are fairly easy to clear.įirst, tap the bottom of the magazine and make sure it is fully seated into the gun’s frame. Failure to FeedĪ failure to feed occurs when you fire a gun and the spent round is ejected, but the new round gets stuck and prevents the firearm from returning to the firing position. It’s important to know the different ways your gun can misfire and how to clear a jam when it happens. Just like there can be various reasons for your car not to start, there isn’t any one reason a firearm may jam. While this may sound pretty straightforward, there are actually a number of different types of gun jams that can occur. “A jam could be a stoppage or a malfunction depending on what caused the gun to quit working.” “Often when describing a firearm that has stopped working in the middle of a shooting cycle, it is referred to as a jam,” according to NRA Shooting Illustrated. So, once in a while, it can misfire or jam. Your gun contains many moving parts and is subject to friction and stress. When a gun, no matter what kind or manufacturer, is not regularly cleaned, lubricated, and maintained, it can malfunction just like your car. Firearms are also machines that need to be cared for. or it will run into some mechanical issues. You have to regularly get the oil changed, top off the transmission fluid, etc. Why Do Guns Jam?īefore we can talk about how to handle a jammed gun, we have to go over what causes a misfire so you can hopefully prevent one in the first place.įor your car to run smoothly, it must be well taken care of. Let’s go over the basics of what causes a gun to jam and what to do if you find yourself in that situation. Proper maintenance, lubrication, and care can help prevent jams, but this frustrating occurrence can happen to anyone – so practice is critical. If your weapon malfunctions or misfires in a self-defense situation, you need to know how to quickly and safely clear the gun and continue to defend yourself and those around you. Part of handling a firearm responsibly means knowing how to clear a jammed gun. With the team at Jaw Drop Games having heard the feedback from players and promising to support the game with content in the future, which I hope they stick with in the long run, Gun Jam should be able to eventually join the list of good rhythm games that its promising beginnings seem to exhibit.Anything with moving parts can jam or have mechanical malfunctions. Even despite that unfinished feeling, rhythm fans will most likely enjoy and appreciate what is available and what the developers are moulding. The soundtrack is top-notch, an absolutely great set of head-banging tunes. Gun Jam feels like the game is a few updates away from being a good rhythm-based shooter hybrid because what is here is fun to play. That said, what is here shows the foundations of the game’s mechanics and quality. There are elements that clearly should be featured, tutorials, and ways to look at high scores, that are criminally missing that hurt the overall presentation, while the limited stages and song count hurt the general package. It is hard to ignore Gun Jam’s lack of content in its current state, as it feels like the game should be in Early Access now rather than fully released. 5/12/2024 0 Comments Adcs ema loginSystemic anaplastic large cell lymphoma (sALCL) after failure of at least one prior multi-agent chemotherapy regimen.Classical HL at high risk of relapse or progression as post auto-HSCT consolidation treatment.Classical Hodgkin lymphoma (HL) after failure of autologous hematopoietic stem cell transplantation (auto-HSCT) or after failure of at least two prior multi-agent chemotherapy regimens in patients who are not auto-HSCT candidates.The drug is also approved for the treatment of patients with: Food and Drug Administration for the treatment of adult patients with primary cutaneous anaplastic large cell lymphoma ( pcALCL) or CD30-expressing mycosis fungoides (MF) who have received prior systemic therapy (treatment that reaches and affects the entire body). Hodgkin lymphoma, systemic anaplastic large cell lymphomaīrentuximab vedotin (Adcetris® Seattle Genetics) is approved by the U.S. * In November 2022, after an update from the phase 3 DREAMM-3 study the use of belantamab monotherapy for previously treated patients with relapsed or refractory multiple myeloma was pulled from US market authorization by request of the US Food and Drug Administration (FDA). Access & reimbursement enrollment form (United States Only).Blenrep REMS (Risk Evaluation and Mitigation Strategy).The recommended dosage is 2.5 mg/kg as an intravenous infusion over approximately 30 minutes once every 3 weeks (Q3W). Continued approval for this indication may be contingent upon verification and description of clinical benefit in a confirmatory trial(s). This indication is approved under accelerated approval based on the response rate. Developed disease recurrence during or within six months of completing adjuvant therapyīelantamab mafodotin-blmf (Blenrep™ GSK) is a B-cell maturation antigen (BCMA)-directed antibody and microtubule inhibitor conjugate indicated for the treatment of adult patients with relapsed or refractory multiple myeloma who have received at least 4 prior therapies including an anti-CD38 monoclonal antibody, a proteasome inhibitor, and an immunomodulatory agent.Received prior therapy for metastatic disease, or.healthcare professional, do not continue on this page.Īdo-trastuzumab emtansine (Kadcyla® Genentech/Roche), as a single agent, is indicated for the treatment of patients with HER2-positive (HER2+), metastatic breast cancer (MBC) who previously received trastuzumab and a taxane, separately or in combination. Food and Drug Administration (FDA) and intended for U.S. The information on this page is limited to commercially available antibody-drug conjugates approved by the U.S. |